Research With Adult Stem Cells Improve

This subject reminds me of Christopher Reeve, the former Hollywood actor who became an adviser on stem cell research, claiming scientists were on a brink of a major breakthrough using embryo stem cells. Some friends of mine hated the fact that Bush refused to endorse and fund embryo stem cell research using new embryo stem cells rather than a few existing ones. This is why hype in scientific research must be met with caution rather than making it political. The Hwang scandal in 2004, bares this out as well! Years later, all that hype was not justified! Similar to many claims about evolution! They figured evolutionary explanations about the past had so much success in keeping in the box, why couldn’t embryo stem cell research?

 

Adult stem cell research has grown by leaps and bounds, destroying such arguments made by the former adviser on stem cell research, Christopher Reeve and political figures like John Kerry.  If scientists decided to stay in the box with Reeve and Kerry’s ideals on stem cell research along with other scientists, then two years later Yamanaka’s breakthrough with reprogramming adult stem cells wouldn’t have never happened! A year later Scientific American reported…

“The end of the politically explosive, decadelong ethical battle over human embryonic stem cells may finally be in sight. Two groups of researchers report today that washing human skin cells in similar cocktails of four genes enabled them to reprogram the cells to resemble those harvested from embryos. The finding potentially paves the way for scores of labs to generate new stem cell lines without cloned embryos, which had long been considered the only realistic way of making human stem cells in the short run.”

No embryos required! Imagine that, only two years later after Kerry’s speech about Reeve. Other Adult stem research as discussed in this blog, became the year’s breakthrough in science. But reprogramming adult stem cells didn’t put itself in a box, rather scientists have now discovered another new method. And that method is using “stress”, although stress is not good for the heart, it’s good for reprogramming stem cells, says Sasai and Obokata, two Japanese researchers who used a modest acid bath to create stress with the most fit animal on the planet who can survive extreme conditions and that is the bacterium. Once exposed to the acid bath, the bacterium’s cells revert back to the embryonic stage but even more so than using  Yamanaka’s method.

Using a stress method is logical, especially knowing that the body is able to repair damage tissue. Regenerative medicine has a ways to go but is showing tremendous progress outside of the politically correct box!

 

 

Adult Stems Cells Renew Themselves

Scientists conducted a study on mice which had limb muscle tissue damage. There are adult stems cells known as MusSC which under the membrane that surrounds muscle fibers. These stems cells repair tissue damage.

Scientists used MusSC to transplant into the mice. In order to be successful the transplant had to be accepted by the mice’s bodies. A rejection of the adult stems cells would make the study unsuccessful.

But the MusSC was not rejected, thus the damage was able to be repaired! Quite amazing!

The regenerated tissue, setting off massive waves of muscle cell growth and repair, and subsequently showed that the MuSC and descendents rescued the second animal’s lost muscle healing function.”

“Scientists, Alessandra Sacco and Helen Blau, had genetically engineered the transplanted MusSC to express Pax7 and luciferase proteins. As a result, every transplanted cell glowed under ultraviolet light and was easy to trace.” Science Daily

Just being able to detect the presence of these cells was very remarkable. It’s a continuing list of great success stories of adult stem cell research. Sadly, the new administration coming into office wants more focus on ES.

“U.S. researchers are eagerly anticipating the moment that President-elect Barack Obama takes office and sweeps away the Bush Administration’s restrictions on federal funding for research with human embryonic stem (ES) cells.  Scientists at the U.S. National Institutes of Health (NIH) are making no secret of their glee.  “I think everybody here is incredibly excited about the new Administration,” says Story Landis, director of the National Institute of Neurological Disorders and Stroke and chair of the NIH Stem Cell Task Force.”

Clearly these scientists have no ethical problems with their obsession with embryonic stem cells. One nurse told me, “well they are throwing out ES anyway, so why not used them?” Adult stems cells have shown and continue to show more progress in treatment.

As I pointed out in a previous post on this subject, embryonic stems cells are money makers for research. Now it appears in more ways than one!

California Institute for Regenerative Medicine which is known as the embryonic stem cell institute approved by voters was given a gift from the State. According to the California’s state stem-cell agency, the chairman’s request for a half-million dollar salary was granted.

With California having a deficit crisis, this news as you might imagine to sit too well. Overpaying people doesn’t always happen in the private sector, it also happens in government agencies.

But anyway, back to better news, the break though in the transplant that repaired tissue was remarkable, and I would encourage any Christian out there who is thinking going into the  medical field, you might want to consider adult stem cell research!

Regenerative Medicine Finding More Potential in Adult Stems Cells

I have been following this story since early September about the advancement in progress of adult stem cells. During this election year, more attention has bee focus on the likes of McCain/Palin in particular about embryonic stem cell research rather than adult stem cell research. It’s a political bias rather than a scientific one.

Militant evolutionists claim creationists have a hard time absorbing new information, I believe it’s the opposite. Their concerns and criticisms on creationists being against destroying the embryo which is human life for stems cells is unwarranted.

But the debate about embryonic stem cell research is falling by the wayside since 2001. More potential in adult stems cells has been steady progressing.

“The scientists, led by Bruno Péault, PhD, deputy director of the Stem Cell Research Center at Children’s Hospital, identified cells known as pericytes that are multipotent, meaning they have broad developmental potential. Pericytes are found on the walls of small blood vessels such as capillaries and microvessels throughout the body and have the potential to be extracted and grown into many types of tissues, according to the study.” Science Daily

“This finding marks the first direct evidence of the source of multipotent adult stem cells known as mesenchymal stem cells. We believe pericytes represent one of the most promising sources of multipotent stem cells that scientists have been searching for in the quest to make regenerative medicine possible,” Dr. Péault said.” Science Daily

Very promising news indeed in the world of regenerative medicine.  It’s one of the few articles that doesn’t try and explain how evolution accomplished the mesenchymal stems cells through computer simulations or by other means. The story of adult stem cell research will continually be followed up on as new discoveries warrant it. And one more very promising news bit…

“Dr. George Q. Daley of Boston’s Children’s Hospital told LifeNews.com that these adult stem cells are disease-specific and “offer an unprecedented opportunity to recapitulate both normal and pathologic human tissue formation in vitro, thereby enabling disease investigation and drug development.”

Stem Cell Research Shifting Focus

Embryonic stem cell research is now fading as it showing less and less promise. However, adult stem cell research since last year has been showing remarkable progress.  Embryonic stem cell research remains highly controversial for many including myself. The research was promoted on a large scale as the new vehicle of future treatments for diseases. It became a political issue just a few years ago. Biotech companies pushed hard for easing restrictions on embryonic research. President Bush addressed the push for this expansion in the following speech given on Aug 9, 2001…

“Based on preliminary work that has been privately funded, scientists believe further research using stem cells offers great promise that could help improve the lives of those who suffer from many terrible diseases — from juvenile diabetes to Alzheimer’s, from Parkinson’s to spinal cord injuries.  And while scientists admit they are not yet certain, they believe stem cells derived from embryos have unique potential.”

Christians alike including myself opposed the idea of embryonic research because of it’s dealings with a human life which God created. But it wasn’t necessarily a total non-endorsement against the research itself. There were other ways in obtaining embryonic stem cells such as the umbilical cords. Liberals were outraged over Bush’s limited use of the research. Evolutionary scientists were bent on destroying embryos.

In 2007, it was reported in science daily“Adult stem cells, found in many tissues in the body, are precursor cells for specific cell types. For example, stem cells found in the bone marrow develop into blood cells, bone cells and other connective tissues, and neural stem cells develop into brain tissue.” In August 2008 there has been major progress on what is called; pluripotent stem cells which are made from adult stem cells. The progress has been so profound, showing much promise that researchers are loosing interest in embryonic research which “almost has no therapeutic advances to show for the cash.” Yes, embryonic research was “big business” at one time and entailed sinful behavior over destroying the embryo. In fact it still is to a certain degree big business as it remains political. Congress and both candidates Obama and McCain support expansion of this dying research. Perhaps both candidates and many others who supported it from the past should shift the focus now to things like pluripotent stem cells and even cell transmogrification.

There has been some good news on the cell transmogrification front which has scientists excited but are still years away on making any major advancement (if any) on this particular cell research;In a discovery that’s being hailed as a leap forward in regenerative medicine, researchers have found a way to transform common pancreatic cells in an adult mouse into the rare, insulin-producing beta cells that are destroyed in type 1 diabetes. There are always high expectations of cures and treatments in the beginning. Only time will tell if this will pan out into a real breakthough among humans, but one thing is for sure, there is a shift in stem cell research.