Genome Lacks Compliance With Evolutionary Theory

Normally evolution does well with certain models along with assumptions (without observational data).  But according to a new research paper in nature not even models which hold to certain assumptions confirm evolution!

Four  universities conducted research on contemporary human populations in order to discover advantageous mutations, along with the rate of degradation by mutations. Trying to understand diseases from the present is one thing, it’s quite another trying to obtain knowledge of historical evolution which goes by the assumption of many millions of years.

In nature

“Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants…We estimate that approximately 73% of all protein-coding SNVs [single-nucleotide variants] and approximately 86% of SNVs predicted to be deleterious arose in the past 5,000–10,000 years. The average age of deleterious SNVs varied significantly across molecular pathways, and disease genes contained a significantly higher proportion of recently arisen deleterious SNVs than other genes.”    

 The researchers used the term “explosive population growth” because of its long age assumption whereby,  “selection has not had sufficient time to purge them from the population.” Researchers then claim that Europeans had stronger genetic drift, than Africans which is strange because genetic drift doesn’t know the difference. Obviously, they are fudging their assumptions in more ways than one!

They give an assessment of their findings…

“More generally, the recent dramatic increase in human population size, resulting in a deluge of rare functionally important variation, has important implications for understanding and predicting current and future patterns of human disease and evolution.”

“For example, the increased mutational capacity of recent human populations has led to a larger burden of Mendelian disorders, increased the allelic and genetic heterogeneity of traits, and may have created a new repository of recently arisen advantageous alleles that adaptive evolution will act upon in subsequent generations.

Advantageous mutations? Where are they? The researchers provide no examples in which they observed! They merely assumed it, because it’s part of evolution! This is what you call, “circular reasoning!” If the supposed evolutionary past doesn’t add up with the present data, how is this shed light on future patterns for evolution? When a theory displays a considerable pattern that shows increasing complexity in its explanation, the theory is not valid!

Rather than observing advantageous mutations, they observed a “larger burden of Mendelian disorders” afflicting mankind which is vital for understanding diseases not evolution. The research does however confirm a creation scientist’s (John Sanford) proposal which is known as genetic entropy where the genetic load increases dramatically. That would be a problem for evolution, because that observation makes it impossible for mankind to survive tens of thousands of years!

Here is more on the genome in this interview with John Sanford…

And here is part two of the interview with John Sanford…

The researchers are baffled by their finding as one can read by what they expected in the evolutionary framework verses what they observed!

“The site frequency spectrum (SFS) of protein-coding SNVs revealed an enormous excess of rare variants (Fig. 1a). Indeed, we observed an SNV approximately once every 52 base pairs (bp) and 57 bp in European Americans and African Americans, respectively, whereas in a population without recent explosive growth we would expect the SNVs to occur once every 257 bp and 152 bp in European Americans and African Americans, respectively (Supplementary Information).”

Thus, the European American and African American samples contain approximately fivefold and threefold increases in SNVs, respectively, attributable to explosive population growth, resulting in a large burden of rare SNVs predicted to have arisen very recently (Fig. 1b).”

“For example, the expected age of derived singletons, which comprise 55.1% of all SNVs, is 1,244 and 2,107 years for the European American and African American samples, respectively. Overall, 73.2% of SNVs (81.4% and 58.7% in European Americans and African Americans, respectively) are predicted to have arisen in the past 5,000 years. SNVs that arose more than 50,000 years ago were observed more frequently in the African American samples (Fig. 1b), which probably reflects stronger genetic drift in European Americans associated with the Out-of-Africa dispersal.”

 Their findings conflict with the whole long ages notion which comes from the ‘theory’ of evolution but does shed light on understanding diseases better while containing evidence for a population that has been around for 5,000 to 10,000 years! Which confirms what? Yes! It confirms creationism!

Creationism’s Predictions vs Evolution’s Predictions

Creationism predicts genetic entropy in nature, which means the DNA for humans was much better with the ancients than it is today while evolution predicts gains in function with the purpose of enhancing fitness. There was a study recently with Vitamin C which is interesting, because humans have lost the ability to manufacture it, so it must be obtained through a diet. And we are not the only ones, certain bats, and certain birds, some fish, guinea pigs and anthropoid have also lost the ability to manufacture Vitamin C.

The study was focused on why this has happened, in PLoS they say, “The ability to synthesize Vc has been reported in many ancestral vertebrate lineages, suggesting the ability for de novo synthesis is ancient.” Nowhere in the paper do the authors explain for the most part on how Vc emerged in the first place such as gains in function within various transitional forms. Rather, the paper mentions quite a bit on loss of function.

“Interestingly, ancestral sequence reconstruction exhibits a stepwise mutation pattern (figure 4) that starts around the time when the tested bat species first evolved from a common ancestor around 58 mya.”

“The ancestor of all bats maintains most of the original Laurasiatheria gene form (with only two mutations) after divergence with non-bat Laurasiatheria species; the ancestor of Hipposideridae, Rhinolophidae, and Megadermatidae (origin around 52 mya) has 3 mutations; the ancestor of Hipposideridae and Rhinolophidae (origin around 39 mya) has 4 mutations; the ancestor of Pteropodidae (origin around 23 mya) has 7 mutations; and the ancestor of the recently emerged Pteropus bats (around 3 mya) have 13 mutations, hence showing a stepwise accumulation of mutations during bat GULO evolution.”

They assume the evolutionary dating, but all this is showing is how many mutations a species had rather than gains that transforms the animal into a bat, what they are showing is the number of mutations with loss in function. Is this really evolution? Wouldn’t it be better for the body to already have the supplement instead of having to obtain it through diet? If any thing, the prediction of evolution would be the other way around. All this study consists of mutations taking away function. Their answer, well the humans and animals can eat, so it wasn’t necessary to manufacture the supplement.  It is interesting to note, the paper mentions, the ancestor of all bats” but there is no common ancestor of bats! They just assume it because where is it? The oldest bat fossil is one hundred percent bat!

In another study from last year, Peter A. Lind, Otto G. Berg, and Dan I. Andersson from Uppsala University conducted an experiment on Salmonella bacterium which was published in the journal of science in November 2010. Their focus here was to come up with new insights on how evolution increases fitness. What surprised evolutionists about this experiment, the mutations caused a loss in fitness rather than an increase in fitness which also confirms the creationist prediction of genetic entropy in nature!

In another paper in Nature, “Experimental evolution reveals resistance to change” where it says…

“Experimental evolution systems allow the genomic study of adaptation, and so far this has been done primarily in asexual systems with small genomes, such as bacteria and yeast.  Here we present whole-genome resequencing data from Drosophila melanogaster populations that have experienced over 600 generations of laboratory selection for accelerated development.”  We conclude that, at least for life history characters such as development time, unconditionally advantageous alleles rarely arise, are associated with small net fitness gains or cannot fix because selection coefficients change over time.”

Science continues to confirm genetic entropy in nature and scientists are now taking a look at on how they they could restore the body being able to make  Vitamin C again. “The gene encoding GULO in guinea pigs and humans has become a pseudogene.” Wouldn’t that be great? No more having to ingest Vitamin C anymore!

The End of Human Evolution: Leading Geneticist Says

“Professor Jones will argue that there were three components to evolution – natural selection, mutation and random change. “Quite unexpectedly, we have dropped the human mutation rate because of a change in reproductive patterns,” Professor Jones told The Times.”

A shortage of fathers and since there is a shortage of fathers, there is not enough genetic mistakes (Mutations) which are copied generation after generation which rarely gets corrected by natural selection according to Jones. It’s highly unlikely Steve would admit, but he starting to prove indirectly the Second Law of Thermodynamics…

“Human evolution has neither stopped, nor speeded up. Nor has it continued at the same pace. It has simply never taken place to begin with.” Creation on the Web

Information goes downward not upward. When Adam and Eve were designed by God, their genetic information was perfect. After the fall (man’s first sin), mutation errors started so then after each generation many genetic errors from the past were inherited.

I have gone into this subject of mutations in detail which is evolution’s last explanation on how one species can turn into a completely different species or enhance an existing species with brand new information. I agree, genetic change is still very much a part of humanity but is limited in scope as information moves  naturally downward not upward. Nature cannot go beyond natural laws so there is no possible way information would go upward.

Some say it’s not surprising for an evolutionist to come up with such a conclusion; “Evolution is over”  but I think it is somewhat surprising, I know it’s been discussed before, but I seen stranger things from various backgrounds in the secular scientific community.