Adult Stem Cell Research Reaching New Highs

Remember back in 2006, President Bush for the first time used his veto power on bill that would have  loosened the restrictions on federal funding for embryonic stem-cell research?  House Republican leaders broke ranks and attempted to override the President’s veto but fell short.

Remember how anyone opposed to ES research were portrayed as uncaring, and unloving which hindered the progress of science that would have found possible cures for certain diseases? Do you remember the tear-jerking commercials by Hollywood celebrities suggesting that only embryonic stem cells provided hope for cures to Parkinson’s and other crippling diseases?

Finally in 2009, Democrats with some Republicans and liberal scientists got what they wanted from Obama and the funding restriction was lifted.  So whatever happened to the rush for embryonic stem cell therapies once the restrictions for funding were lifted by President Obama? Induced pluripotent stem cells has practically replaced the need for embryonic stem cells.

Did you know embryonic stem cells have yet to produce one treatment? Adult stem cell research has been showing remarkable progress and was voted as the number one breakthrough in science for 2009! The bulk of the funding is now being channeled in this particular area of research which would make a lot of sense.

The first break through for 2010 was conducted with using stem cells from a unbilical cord in treating leukemia, it was deemed the first success story by science daily

“In a study published in the Jan.17 edition of Nature Medicine, Colleen Delaney, M.D., and colleagues describe the first use of a method to vastly expand the number of stem/progenitor cells from a unit of cord blood in the laboratory that were then infused into patients resulting in successful and rapid engraftment.”

“Despite the numbers disadvantage, cord blood is a promising source of stem cells to replace diseased blood and immune systems in stem cell transplantation because the donated cells don’t need to be perfectly matched to the patient.”

“The lack of a suitable match is why about 30 percent of patients overall who need a stem cell transplant to treat cancers such as leukemia can’t find suitable donors. Among racial-minority patients the number who cannot find suitable donors is about 95 percent.”

This is absolutely great news! It goes to show how Hollywood and liberal scientists made this issue concerning ES research while making promises that had no idea what they were talking about plus they were neglecting other alternatives in stem cell research which made it very political because it was against the Bible and conservative Christians. It’s quite possible, that adult stem cell research could be once again the breakthrough in science for 2010!

Scientists No Longer Avoid Inserting Reprogrammed Genes Into Chromosomes

What is been labeled “ethical stem cell research” which is adult stem cell research, has had another break through again. Using retroviruses to insert into the genes from a mouse and human skin cells causing them to revert back to their embryonic state (known as induced pluripotent stem cells).

Reprogramming genes into the chromosomes has been avoided up until now with the latest research as reported in New Scientist…

“Last year, for instance, a team led by Konrad Hochedlinger of the Massachusetts General Hospital in Boston put the reprogramming genes into adenoviruses, which live for only a short while in a cell and don’t normally jump into its chromosomes. The technique worked in mouse liver cells – but was very inefficient.”

“Now two groups of researchers have taken a different approach, using a system that puts the genes into chromosomes, but allows them to subsequently be removed.”

“Rather than using viruses, the researchers instead turned to a “transposable element” known as piggyBac. Originally found in insects, piggyBac is a parasitic stretch of DNA that can move around the genome, cutting and pasting itself into a chromosome where the genetic sequence reads “TTAA”.

The new method allowed scientists to study those cells (piggyBac) which had only a 40 percent chance of reinserting themselves back in the chromosomes.

“Whether the method catches on may depend on rival researchers’ success in attempts to devise simpler methods that don’t require the reprogramming genes. For instance, Sheng Ding of the Scripps Research Institute in La Jolla, California, is experimenting with reprogramming using small-molecule drugs.”

One of the rare articles, that deals with scientific studies which doesn’t try to explain it by using evolution. In fact, the theory of evolution is not needed in these experiements. A breath of fresh air, but also what’s also exciting is the fact that advancements in this type of research is progressing well which may lead to much better treatments for cancer!