Adult Stem Cell Research Reaching New Highs

Remember back in 2006, President Bush for the first time used his veto power on bill that would have  loosened the restrictions on federal funding for embryonic stem-cell research?  House Republican leaders broke ranks and attempted to override the President’s veto but fell short.

Remember how anyone opposed to ES research were portrayed as uncaring, and unloving which hindered the progress of science that would have found possible cures for certain diseases? Do you remember the tear-jerking commercials by Hollywood celebrities suggesting that only embryonic stem cells provided hope for cures to Parkinson’s and other crippling diseases?

Finally in 2009, Democrats with some Republicans and liberal scientists got what they wanted from Obama and the funding restriction was lifted.  So whatever happened to the rush for embryonic stem cell therapies once the restrictions for funding were lifted by President Obama? Induced pluripotent stem cells has practically replaced the need for embryonic stem cells.

Did you know embryonic stem cells have yet to produce one treatment? Adult stem cell research has been showing remarkable progress and was voted as the number one breakthrough in science for 2009! The bulk of the funding is now being channeled in this particular area of research which would make a lot of sense.

The first break through for 2010 was conducted with using stem cells from a unbilical cord in treating leukemia, it was deemed the first success story by science daily

“In a study published in the Jan.17 edition of Nature Medicine, Colleen Delaney, M.D., and colleagues describe the first use of a method to vastly expand the number of stem/progenitor cells from a unit of cord blood in the laboratory that were then infused into patients resulting in successful and rapid engraftment.”

“Despite the numbers disadvantage, cord blood is a promising source of stem cells to replace diseased blood and immune systems in stem cell transplantation because the donated cells don’t need to be perfectly matched to the patient.”

“The lack of a suitable match is why about 30 percent of patients overall who need a stem cell transplant to treat cancers such as leukemia can’t find suitable donors. Among racial-minority patients the number who cannot find suitable donors is about 95 percent.”

This is absolutely great news! It goes to show how Hollywood and liberal scientists made this issue concerning ES research while making promises that had no idea what they were talking about plus they were neglecting other alternatives in stem cell research which made it very political because it was against the Bible and conservative Christians. It’s quite possible, that adult stem cell research could be once again the breakthrough in science for 2010!

Stem Cell Research Remains Controversial And Promising

Obama’s unbiblical executive order doesn’t  not specify the source of the embryos which means scientists are free to work on any embryos including  human embryos created solely for research purposes.

Even with the restrictions lifted, it remains a political battle ground on ethics so the distinction is not normally labeled properly by proponents of ES instead, they refer to it as just “stem cell” research. Science labels it like something out of the occult, “The Enlightenment Returns.”

On the flip side, adult stem cells continues it’s rampage in progress. Science Daily reports…

“Preliminary data presented on March 28 as a late-breaking abstract at the American College of Cardiology’s 58th annual scientific session from the largest CD34+ adult stem cell study for heart disease has shown the first evidence that delivering a potent form of autologous (from the patient) adult stem cells into the heart muscle of patients with severe angina may result in less pain and improved exercise tolerance.”

More treatments include, progress in adult stem cells concerning diabetics as reported in PhysOrg…

“Hess drew human bone marrow and simultaneously isolated three different types of stem cells that co-ordinate together to form new blood vessels. These are called pro-angiogenic stem cells. They were purified to remove any inflammatory or contaminated cells, and then injected into the circulation of mice which had one of their leg arteries ligated and removed.”

“The researchers showed how these stem cells have a natural ability to hone in on the area of ischemia to induce blood vessel repair and improve blood flow. Hess says this research is clinically-applicable because they studied the function of human stem cells in immune-deficient mice.”

“The preclinical data from Hess’ research was used by a biopharmaceutical company, Aldagen to receive FDA approval for a multi-center clinical trial now underway in Houston, Texas, involving 21 patients with end-stage peripheral artery disease.”

Many scientific organizations are liberal, they reject ethics and mislead the public by not making the distinctions with their labeling between adult stem cells and ES. Obama didn’t restore science. Bush allowed more ES research than Clinton did. This is all highly political with no morality with these organizations who should be demanding more money for adult stem cell research as well as praising the remarkable progress in this area.

Obama’s Policy Shift: Lifting The Ban On Embryonic Stem Cells

I can remember a friend of mine who’s husband was sick and his condition was getting progressively worse. As we were voice chatting over the internet with a group of other friends, while talking about her husband (which is also a friend of mind) she got extremely angry at Bush who was the President at the time. In her emotional state,  I can understand her desire for wanting her husband to get better and adult stem cell research at that time hadn’t taken off yet but there was a lot of hype about ES in the media and as a result, she lashed out at Bush for banning Embryonic Stem Cell research. What she didn’t know or may have forgotten, Bush was just reaffirming the old Clinton policy of not using taxpayer dollars for the research, but as for the ES research itself, it wasn’t banned at all.

“James Thompson, the stem cell pioneer from the University of Wisconsin who was the first to grow human embryonic stem cells in 1998, is an independent codiscoverer of iPS cells along with Japanese scientists. Already these reprogrammed cells have eclipsed the value of those harvested from embryos, he has said, because of significantly lower cost, ease of production, and genetic identity with the patient. They also bring unique application to medical and pharmaceutical research, because cells cultivated from patients with certain diseases readily become laboratory models for developing and testing therapy. That iPS cells overcome ethical concerns about creating and sacrificing embryos is an added plus.” -USN

Indeed, there are ethical concerns but not all ES collections involving the killing of an embryo (a human being) but there is so much more promise and progress with adult stem cells. Recently, science daily reported another breakthrough with adult stem cells that will help treat Muscular Dystrophy in the future.

“The research team, which is based at UNSW and formerly from Sydney’s Westmead Children’s Hospital, adapted a technique currently being trialled in bone marrow transplantation. Adult stem cells are given a gene that makes them resistant to chemotherapy, which is used to clean out damaged cells and allow the new stem cells to take hold.”

Not only is adult stem cells showing promise in the area of  Muscular Dystrophy but there are new and safer ways being developed in reprogramming these important cells of the body. Also the discovery of new methods in creating stems cell could lead to to vital treatments and possible cures for fatal or very disabling diseases…“This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues such as a patient’s own skin cells.”

Maintaining the behavior of adult stem cells acting as though there were still in the embryonic stage (iPS cells) is a very critical piece for treating such things as Parkinson’s disease. Scientists have shown progress in this area…

“Until this point, it was not completely clear that when you take out the reprogramming genes from human cells, the reprogrammed cells would actually maintain the iPS state and be self-perpetuating,” says Frank Soldner, a postdoctoral researcher in Whitehead Member Rudolf Jaenisch’s laboratory and co-author of the article.”

One of the major advantages of using adult stem cells, it eliminates the threat of the body rejecting the cells. In any transplant there is a risk of rejection, but if one is able to create stem cells from the patient, it will certainly hold more promise and have a greater success in treating patients than using stems cells from another person.

How many treatments as adult stem cell research produced? The results speak for themselves, the answer is 74 different treatments for various diseases. On the other hand, how many treatments has embryonic stem cell research produced? The answer is; none. Yep, you got it, not one single treatment. This is not to say, it’s going to be a cure all for everything. There might be some problems down the road, but my point is this, there is more promise with this new technology than with embryonic stem cell research, and it avoids the ethical issue of killing an unborn person.

Obama’s policy shift from two previous Presidents (Clinton and Bush) is hailed by the liberal establishment as restoring “scientific integrity.” And what many do not know, the shift in policy lifts mandated funding for adult stem cell research! This means there is a cut in funding for adult stem cell as the well could dry up in some areas in this research. When the government is not mandated it becomes selective, and depending on who is in office, the funding changes.

Is scientific integrity for a doctor who had to leave the US because he could not get the funding needed for his adult stem cell research for spinal cord injuries? Is reducing funding for heart patients using adult stem cells “scientific integrity?”

“One of his congestive heart failure patients was Dr. Howard Lindeman, a heart attack victim who says he has been given a new life- “I had the procedure done and since then, I’ve just been getting better and better and better. I’m going to be 58-years-old in May and I’m on my way to being 35 again,” he said.”

Here is another success story about those who heart problems being treated in other countries while the United States has been behind in this area due to all the regulations the treatment has to go through before being approved which takes years.


There is an astounding number of success stories about adult stem cell research, that I’m unable to list them all on this page with any great detail but it’s absolutely amazing in such a short period of time, the progress being made with adult stem cells.

Is it scientific integrity to reduce funding for 74 or more promising treatments? The Obama shift in policy in stem cell research is not about getting people better treatments for various diseases but only what is politically correct in the liberal part of the scientific establishment who not only helped him get into office, but are  just so bent on rebelling against God!

Latest News Buzz In The Realm of Science

Creation Ministries held one of their biggest conferences ever. People from all all over the world attended. Those who spoke at the conference were population geneticist Prof. John Sanford, marine biologist/geneticist Dr Robert Carter, geophysicist and plate tectonics expert Dr John Baumgardner, Archeologist David Down, physicist-cosmologist Dr John Hartnett and CSIRO, tree researcher Dr Geoff Downes.

“There were some remarkable presentations about the latest findings in genetics that showed how the most recent information in the world database of the human genome can be used to test various scenarios about human history, such as naturalistic evolution, progressive creation and the biblical creation-flood-Babel model. They showed that the latest genetic information supports the biblical history through the evidence of the variation in the Y chromosome, mitochondrial DNA and the X chromosome.”

“In addition, there have been some remarkable genetic discoveries that have totally transformed genetic ideas, even those published as recently as 5 years ago. In fact, Dr John Sanford, showed how the latest information about genetic mutation rates in the human genome ‘clearly falsifies’ the central axiom of today’s evolutionary biology, the neo-darwinian mechanism.”

In other news, Evolution is loosing the PR War…New Zogby poll shows a growing support for teaching “strengths and weakness” of evolution in public school classrooms, which is up nine percent from a previous poll conducted in 2006.

In another poll, reported by Fox News only 4 in 10 people actually believe in evolution. Even with the massive indoctrination, and the pull evolutionary science has in government schools, as well as 10,000 so-called Pastors who went public by stating their support for evolution (in honor of Darwin’s birthday) as well as the Vatican, it has failed in an enormous way to convince the public that it’s the best science, and the Bible is wrong.

More news includes economics, we are in a worldwide ressession and it’s taking it’s toll on evolutionary biology. There are shifts going on with tight budgets. Nature reports that the Netherlands has cut it’s staff in the area of evolutionary biology in a major way and is being replaced with jobs for molecular biology which can attract more grants. Ronald Plasterk who is the minister of science says the changes are to induce competition in the scientific community.

And lastly, more great news concerning adult stem cell research which might reduce the need for heart transplants!

“Heart disease patients in England who may otherwise need a transplant could soon participate in a trial involving the use of adult stem cells that may reduce or eliminate the need for the transplant. The trials, if successful, could show another capability of the ethical version of stem cells.”

Also, UW-Madison shows remarkable progress in adult stem cell research as stated below!

In a study published online Feb. 12 in Circulation Research, (and also reported in science daily) UW-Madison School of Medicine and Public Health professor of medicine Tim Kamp and his research team showed that they were able to grow working heart-muscle cells (cardiomyocytes) from induced pluripotent stem cells, known as iPS cells. The heart cells were originally reprogrammed from human skin cells by James Thomson and Junying Yu, two of Kamp’s co-authors on the study.


Reprogramming Adult Stem Cells Becomes Easier

What was deemed to be the best break through of 2008 in the science community, has started this year where it left off from last year. Reprogramming adult stem cells is becoming easier because instead of using many viruses to reprogram the cells, it uses just one virus which then turns the Adult Stems into Pluripotent Stem Cells. These cells in turn act like as though they were embryonic stem cells.

“The major milestone the six-member research team, led by Gustavo Mostoslavsky, Boston University Assistant Professor of Medicine in the Gastroenterology Section, achieved was combining the four vectors into a single “stem cell cassette” containing all four genes. The cassette (named STEMCCA) is comprised of a single multicistronic mRNA encoding the four transcription factors using a combination of 2A peptide technology and an internal ribosomal entry site (IRES).”

“With the STEMCCA vector, the researchers were able to generate iPS cells more efficiently — 10 times higher than previously reported studies.” Science Daily

Other news about Adult Stem Cells…

On January 8, 2009 in the Journal of Stem Cell reports that scientists are able to induce more adult stem cells into the blood stream using mice. Bone marrow is vital when it comes to diseases or injury. It gathers different types of stem cells to help repair and then regenerate the tissue. Scientists used a combination of drugs that triggered the extra stem cells.

“This study is the first to selectively mobilize mesenchymal stem cells and endothelial progenitor cells from the bone marrow. Previous studies have only been able to mobilise the haematopoietic type of stem cell, which creates new blood cells. This technique is already used in bone marrow transplants in order to boost the numbers of haematopoietic stem cells in a donor’s bloodstream.”  —SB

It’s not known yet in this study if triggering extra stem cells into the blood stream will help the person heal better or in this case mice. I believe the regulation of different stems cells performed bone marrow is key component in this area not just extra stem cells. Certainly triggering more stem cells is worth more study. Looking forward to more advances in adult stem research!

Reprogrammed Stems Cells Opens More Doors For Fighting Diseases

One of the greatest advancements in science this year, if not thee best advancement for 2008, is reprogramming stem cells.

A young boy who has a genetic disease was the subject of the latest research which was published in the journal Nature on December 21, 2008. Using a relatively simple skin biopsy from the 3 year old boy.

“The UW scientists used the reprogramming technique pioneered last year by their UW colleague James Thomson and by Shinya Yamanaka at Kyoto University in Japan, and sent the boy’s skin cells back to the embryonic state. They then grew the reprogrammed cells into motor neurons, the type damaged by the disease.”

motor-neurons

“The Nature paper, a collaboration by seven scientists including Thomson, did include a cautionary note: More work must be done, the authors wrote, “to ensure that reprogramming has not subtly affected the ability of the motor neurons to function normally.”

“Even more promising, though further off, is the possibility that scientists will be able to reprogram the cells of a child with spinal muscular atrophy, correct the genetic defect, then produce healthy motor neurons. The healthy motor neurons could then be injected back into the patient without any danger of rejection.” -JSOnline

Out of all this excitement in the progress of this research, I’m sorry to tell you that the little boy who had contributed to this very important scientific research that someday may help others in the future, had passed away at the age of three years old.

I will be stressing like crazy how it’s way more important to reprogram adult stem cells than to use unethically collected embryonic stems cells.

Here is the a list of some (not all) of the many other promising benefits from adult stem cell research include…

1) Brain Cancer  2) Skin Cancer: Merkel Cell Carcinoma  3) Hodgkin’s Lymphoma 4) Neuroblastoma 5) Corneal regeneration 6) Stroke Damage 7) Chronic Liver Failure and Retinoblastoma

On the other hand, the negatives includes the hype on embryo research has frustrated some experts in the field…

Colin McGuckin, professor of regenerative medicine at Newcastle University and an expert in adult stem cells, this week hit out at both his university and UK funding agencies. He said that they were prioritising embryonic stem-cell research above work with adult stem cells, despite the more immediate clinical benefits offered by his work.”

That’s generally what happens when medicine becomes too political and special interests including the liberal side of the scientific community only have one interest.

In conclusion, nothing in evolution has helped the current progress of reprogramming adult cells. The research as shown above gets overlooked so funding is not at the level it would be. No doubt, more promising future treatments, and studies coming from adult stems cells, so stay tuned!


Dental Pulp Stem Cells Could Be Good For the Brain

Adult stems cells have been found to regenerate many different types of cells. In this new discovery, scientists have found a unique feature in dental stem cells which can stimulate growth of new neural cells, and many of these formed neurons.

Since Obama started running for office up until now where he promised to unban embryonic stem cells research, the focus has been on one aspect of this type of cell research. While very little attention has been paid to the major progress of adult stem cells. You can talk to a person on the street about stem cells and generally what the first thing comes to mind are embryonic stem cells. I believe the general public is not aware enough about this vital research concerning adult stem cells.

The conflict with embryonic stem cells, has created a political circus. Generally, collecting human embryonic stem cells for the most part come from embryos. Once the cells are collected, it then destroys the remaining embryo. There is an alternative in collecting these type of cells, but not enough to satisfy the demand. There is currently a shortage of human embryonic stem cells which can result in paying people to obtain them.

As far as Christians are concern, the embryos are human life no question about it, no science to refute otherwise on when life begins, but to liberals embryos are just a “thing” to work with while promising to find cures for diseases.

Back to the latest discovery of the promising possible impact of dental pulp stem cells which are adult stems cells…

By showing dental pulp stem cells are capable of stimulating growth of neurons, our study demonstrates the specific therapeutic potential of dental pulp stem cells and the broader potential for adult stem cells,” says Chan, who also is assistant professor of human genetics in Emory School of Medicine.

“Because dental pulp stem cells can be isolated from anyone at any age during a visit to the dentist, Chan is interested in the possibility of dental pulp stem cell banking. “Being able to use your own stem cells for therapy would greatly decrease the risk of cell rejection that we now experience in transplant medicine,” says Chan” -Science Daily

Adult stem cells show way more promise and it’s way more versatile. It’s also humane, and helps decreasing cell rejection. You can make a cell regenerate but if it’s rejected, it’s no use to the person who needs treatment. Very exciting to learn about the progress in dental pulp stem cell research, thanks to the Lord!