The number one breakthrough in science of 2009, continues its amazing progress in 2011 with promising treatments with no ethical questions like embryonic stem cell research. A breakthrough in fighting lung disease, physorg reports on how Duke scientists discovered a signal used by airway stem cells that regulate which tissues are produced.
“Our work has identified the Notch signaling pathway as a central regulatory ‘switch’ that controls the differentiation of airway basal stem cells,” said Jason Rock, Ph.D., lead author and postdoctoral researcher in Brigid Hogan’s cell biology laboratory.”
“Studies like ours will enhance efforts to develop effective genetic, cellular, and molecular therapies for airway diseases – a leading cause of death worldwide. Interestingly, the press release likened the Notch signalling pathway to “executive software” governing the stem cells’ fate.”
Some more research consists of a new way to reprogram skin cells directly into brain cells! Science daily reports this particular breakthrough…
“The new technique avoids many of the ethical dilemmas that stem cell research has faced. For the first time, a research group at Lund University in Sweden has succeeded in creating specific types of nerve cells from human skin. By reprogramming connective tissue cells, called fibroblasts, directly into nerve cells, a new field has been opened up with the potential to take research on cell transplants to the next level.”
“The discovery represents a fundamental change in the view of the function and capacity of mature cells. By taking mature cells as their starting point instead of stem cells, the Lund researchers also avoid the ethical issues linked to research on embryonic stem cells.”
Collecting ES stem cells from the umbilical cord blood which hold no ethical dilemmas either, has been a focus of research which shows promise. Where maternity wards, have previously discarded as medical waste, are becoming gold mines for stem cells!
Science daily reports…
“The prototype is still in the testing stage, but initial results are promising. The student inventors have obtained a provisional patent covering the technology and have formed a company, TheraCord, to further develop the technology, which may someday be used widely in hospital maternity units. The students say the need for this system is obvious.
“Cord blood, collected from the umbilical cord and placenta after live birth, is the most viable source of stem cells, yet over 90 percent is uncollected and discarded,” the team members wrote in a presentation of their project at the university’s recent Biomedical Engineering Design Day. “One of the main reasons valuable cord blood is so frequently discarded is because no adequate collection method exists.”
However, it’s not all good news there is some bad news too. Some scientists continue advocating more funding for ES research. Concerns that it might be banned all together which is highly unlikely because not all ES research collected is not ethical rather there is no controversy with collecting and using ES through the umbilical cord and placenta after live birth which are improving with new research. On April 29, a federal appeals court blocked Lamberth’s decision restoring federal financing of human embryonic stem cell research for now. Still some scientists in this field make a faulty argument for their position.
“If federal funding stops for human embryonic stem cell research, it would have a serious negative impact on iPS cell research,” said Stanford University bioethicist Christopher Scott, one of the co-authors. “We may never be able to choose between iPS and ES cell research because we don’t know which type of cell will be best for eventual therapies.”
The research is clear, adult and ips stem cells are the future for treatments, let the evidence lead rather than trying to force taxpayers to fund something that many are not support of, for there is no compelling and logical need to do so!