One of the most important if not thee important parts of our bodies which includes all other living things as well is this amazing enzyme called ATP synthase which is the world’s tiniest rotary motor! Without it, and its function life could not exist. ATP is designed to provide usable energy for cellular machines. Its protein machines power almost everything that goes on inside living cells, including manufacturing DNA, RNA, and proteins, clean-up of debris, and transporting chemicals into, out of, and within cells. Other fuel sources is not able to provide power for these cellular protein machines for the same reasons that oil, or sunlight will not power a gasoline engine.
Logical thinking and common sense about an automobile engine leads us to think that only a clever person (with mind and will) could make this particular machine that is able to convert energy from one form to another for the purpose of moving a car. The machine shows orderly, specified proportions which includes a very clever use of interdependent parts that are the right size, shape and strength to work together for an overall purpose.
Three European scientists, reporting in PNAS cleverly used quantum mechanical approaches to study the amazing enzyme, ATP where they were able to analyze the energy flow during production of ATP in the beta subunits. The alpha subunit rotates like a waterwheel turning a camshaft called the gamma subunit. The authors were able to discover two transition states within the 120° motion that favor the reaction one way, like a ratchet. “These two TSs [transition states] are concluded crucial for ATP synthesis,” they said.
They found that as the enzyme progresses into these states, energy barriers are set up that block the reverse direction, just like a ratchet on a tool. The authors also noted how difficult its getting in studying the ATP, “The complex function of ATP synthase makes this enzyme special compared to many other enzymes and makes computational investigation challenging,” they said.
Many other researchers study the ATP, and a full understanding of the reaction mechanism awaits its discovery in the future, but the authors felt “we have shown how the positions of alpha-S344 and alpha-R373 [two amino acid residues in the active site] may drastically influence the rate and, in this way, attenuate the reversal of these reaction steps.”
It’s no accident that this amazing and highly advanced tiny rotary machine essential to all living things resembles machines produced by intelligence! Even “point mutations of alpha-S347Q and alpha-S347A have dramatic effects on ATP synthase function both for synthesis and hydrolysis.” For the most part evolution wasn’t even mentioned but was mentioned in passing with the claim of learning more about it. Learning about what is happening in the real world is good science which confirms God’s word but attaching a story about evolution to it, doesn’t reveal any light but creates unnecessary speculation.