Papers on biochemistry and biophysics vastly exceed all other topics in science. Major discoveries are being made about how these cellular factories work while evolutionary explanations are used as a passing reference or not mentioned at all which is quite refreshing! These carefully and very advanced built structures speak of design from a mind (God’s in particular) rather than an unthinking process.
Authors in a paper published in Structure…
“DNA polymerases are spectacular molecular machines that can accurately copy genetic material with error rates on the order of 1 in 105 bases incorporated, not including the contributions of proofreading exonucleases.”
On the next paper, we find a pretty amazing journey through several motions when transfer-RNAs and messenger-RNAs traverse the ribosome protein-assembly factory with their amino-acid cargos and genetic data readouts.
The paper reveals details on how the L1 stalks of the ribosome bend, rotate and uncouple – undergoing at least four distinct stalk positions while each tRNA ratchets through the assembly tunnel. For example, “the L1 stalk domain closes and the 30S subunit undergoes a counterclockwise, ratchet-like rotation” with respect to another domain of the factory.
This is not simple. “Subunit ratcheting is a complex set of motions that entails the remodeling of numerous bridging contacts found at the subunit interface that are involved in substrate positioning,” they said. What scientists have learned so far about molecular machines makes the type of chemistry we learned in school very inadequate for understanding the machinery of the cell. For example, interactions between molecules are not simply matters of matching electrons with protons.
Here is another recent discovery where a molecular machine can detect a stretching force when a load is applied…In a paper published in PNAS…
“Some myosin-Is are proposed to act as force sensors, dynamically modulating their motile properties in response to changes in tension.” Why do cells need force sensors? “Tension sensing by myosin motors is important for numerous cellular processes, including control of force and energy utilization in contracting muscles, transport of cellular cargos, detection of auditory stimuli, and control of cell shape.”
The paper had little to say about evolution other than saying it just “evolved.” Biophysics is an area of great scientific study and also it’s where evolution is a useless explanation. On the other hand in Psalm 19:1, “The heavens declare the glory of God; and the firmament sheweth his handywork.” Do you really think evolution created proof reading of errors in the cell so it can survive? Evolution requires flexibility in nature and simplicity, but we don’t observe this. Indeed nature shows it being engineered or designed by intelligence.